Carbohydrate metabolism and disorder. Pathophysiology of diabetes mellitus. Diabetic ketoacidosis, Hyperosmolar non ketotic coma, lactic acidosis, Glycogen storage diseases. Insulinoma. Diagnostic criteria and laboratory investigation. Fasting plasma glucose, random plasma glucose, glucose tolerant test, pancreatic hormones and glycosylated haemoglobin. Lipid lipoproteins structure, composition and function, Intravascular metabolism and catabolism of lipoproteins. Disorders of lipid and lipoproteins. Lipid storage diseases. Cardiovascular function test. Recent advance in diagnosis of lipids disorders. Plasma proteins in health and diseases. Definition, cause and investigation of paraprotein (Bence Jones proteinuria) and significance. Fractionalization of proteins. Protein eclectrophoresis in health and diseases. Protein degradation. Metabolic disorder and regulation of amino acid metabolism.


Level of Study: 500 Level