Theory and practice of clinical cytogentics. Chromosome analysis, structure, organization and staining techniques. Chromosomes in man, Normal karyotype and chromosome abnormalities. Mosaicism, trisomy, monosomy, translocation, Klinefelters and Turner’s

syndromes, sex determination. Genetic diseases, clones, mapping of autosomes, DNA synthesis, gene in kindred segregation, X -linked inheritance. Chimeras. Genes in families and population. Selection, pedigree analysis, mutation and mutagens, Hardy Weinberg equation, genetic drift, inbreed. Slide reporting. Philadephia and Christ church chromosomes.


Level of Study: 500 Level