Prof. S.J. Josiah: Enzymology (3weeks)

General properties of enzymes, coenzymes and cofactors, classification of enzymes , kinetics of enzyme catalyzed reactions, factors that affect the rate of an enzyme catalyzed reaction.  Mechanism of enzyme catalysis.  Regulation of enzyme activities.  Allosteric enzymes, isozymes, multienzymes, importance of enzymology in medicine.

                 

Dr. S.C.O. Nwangwu:    Carbohydrate Metabolism. (3weeks)

Mr. P. E. Osagiede:

Glycolysis, regulation of glycolysis, , TCA cycle, , metabolism of fructose, mannose, galactose. Electron transport chain (energy metabolism)

Glycogen metabolism -    Glycogen synthesis                  (Glycogenesis),-   glycogen degradation     (glycogenolysis), Glyconeogenesis, pentose phosphate pathway, Glyoxylate cycle, Bioenergetics , metabolic rate.

   



 Dr Georgina O Erifeta:    Lipid Metabolism (11/2weeks)

Oxidation and biosynthesis of fatty acids, biosynthesis and degradation of acylglycerols, phospholipids

Dr Georgina O Erifeta:      Lipid Metabolism (11/2weeks)

Lipoproteins &  Sphingolipids in Health & Diseases Lipid storage diseases and their inheritance patterns, sulphatides, globosides, gangliosides and sphingolipids.

Dr. S.C.O. Nwangwu:        

Essential fatty acids and eicosanoids. Clinical applications of eicosanoids and glycolipids. Cholesterol metabolism, steroids, ketosis. 

Dr. S.C.O. Nwangwu:      Protein/Amino Acid  metabolism (2weeks)

Amino acid biosynthesis and catabolism, urea cycle, ketogenic and glycogenic     amino acids.  Creatinine and creatinine  metabolism. Biosynthesis of proteins, inhibitors of protein biosynthesis.

Dr. Helen K. Njoya:   Nucleic Acid  metabolism (2weeks)

Biosynthesis of purine and pyrimidine nucleotides, catabolism of purine, and pyrimidine nucleotides, metabolic disorders of purine metabolism.

Dr Georgina O. Erifeta:  (2weeks) 

Genome structure and organization.  Replication and Transcription of DNA, Repair of DNA, mutation, Abnormalities in Nucleic acid metabolism.  xeroderma pigmentosum and skin cancer.



Level of Study: 200 Level