Definition of Pharmacology, scope and sub-divisions, of Pharmacology, methods and measurement in Pharmacology; drug development and evaluation; biological assays; clinical trails; measurement and evaluation of toxicity, pharmacokinetics; routes of drug administration, kinetics of drug absorption, distribution, blood-brain barrier; placenta barrier, biotransformation and elimination, Pharmacodynamics; mechanics of drug action, drug receptors, signal transduction and second messengers, selectivity of drug action, factors affecting drug action in man. Dose-response relationships, agonists, antagonists and their interactions with receptors. Drug toxicity and adverse drug reactions.

 


Level of Study: 300 Level