Terminal Objectives
The students should be able to:
Define the basic concepts of Pharmacokinetics
Use raw data and derive the pharmacokinetic models and parameters that best describe the elimination.
Critically evaluate biopharmaceutical studies involving drug product bioequivalence and bioequivalence.
Design and evaluate dosage regimens of drug using pharmacokinetic and biopharmaceutical parameters
COURSE OUTLINE
- Definition of Terminology and symbols used in Pharmacokinetics
- Compartment models single and multiple compartment models
Drug Absorption
Bioavailability and Bioequivalence
Drug Clearance
Hepatics Elimination of Drugs
Intravenous Infusions
Multiple Dosage Regimens
Prolonged Action dosage form Administration
Non-linear Pharmacokinetics
- Relationships between pharmacokinetics Parameter and Pharmacologic Response
Pharmacogenetics.
- Lecturer: Paul Isiboge
- Lecturer: Osarugue Uyi